Author

H.-T. Lau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1

Frequent Co-Authors

S.-E. Ong· 3 shared D. J. Maly· 2 shared M. Golkowski· 2 shared A. Lius· 1 shared A. Shoemaker· 1 shared B. Hummer· 1 shared C. S. Asensio· 1 shared H. Kenerson· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBiochemistry

S.-E. Ong

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Author profile →

3 papers

Recent·Most cited

Multiplexed profiling of kinase interactomes quantifies cellular network plasticity

M. Golkowski, A. Lius, T. S. Sapre, H.-T. Lau, T. Moreno, D. J. Maly, S.-E. Ong

The paper introduces Ki-CCA, a method to map kinase PPIs across cancer cell lines, revealing network plasticity and identifying therapeutic targets.

bioRxiv · Sep 14, 2021 · PreprintBiochemistry

Kinome-centric pharmacoproteomics identifies signaling pathways underlying cellular responses to targeted cancer drugs

M. Golkowski, H.-T. Lau, M. Chan, H. Kenerson, V. N. Vidadala, A. Shoemaker, D. J. Maly, R. S. Yeung, T. S. Gujral, S.-E. Ong

The paper develops a kinome-centric pharmacoproteomics platform to identify signaling pathways and biomarkers predicting cancer drug responses and resistance in hepatocellular carcinoma.

bioRxiv · Nov 20, 2019Cancer Biology

CCDC186 controls dense-core vesicle cargo sorting by exit

J. Cattin-Ortola, I. Topalidou, H.-T. Lau, B. Hummer, C. S. Asensio, S.-E. Ong, M. Ailion

This study identifies CCDC186 as a regulator of DCV cargo sorting by exit, showing its role in retaining mature DCV cargos and removing non-DCV cargos post-TGN.

bioRxiv · Nov 6, 2019 · PreprintCell Biology