Author

H.N. Yadav

Indian Institute of Technology Kanpur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Physiology· 2

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Ashish KumariD· 2 shared Hamim ZafariD· 2 shared Rashmi ParihariD· 2 shared Sai Prasad PydiiD· 2 shared Seema Kuldeep· 2 shared Simran Singh· 2 shared Sonal Amit· 2 shared Soumita Bhaumik· 2 shared

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2025-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

Ashish KumarORCID

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2 papers

Recent·Most cited

Myeloid Gi signaling acts as a weight-independent immunometabolic switch controlling systemic insulin sensitivity

Seema Kuldeep, H.N. Yadav, Seema Riyaz, Soumita Bhaumik, Shruti Agarwal, Aishi Satapathy, Simran Singh, Ashish Kumar, Sudipta Paul, Monika Patel, Mriganka De Sarkar, Raashidha Farhath, Sonal Amit, Rashmi Parihar, Hamim Zafar, , Sai Prasad Pydi

This paper identifies myeloid Gi signaling as a weight-independent immunometabolic switch that regulates systemic insulin sensitivity through opposing cytokine programs.

bioRxiv · Mar 31, 2026 · PreprintPhysiology

Acute activation of Gq-signaling in islet macrophages inhibits β-cell insulin secretion through AMPK-sphingolipid axis

Simran Singh, Ashish Kumar, Sudipta Paul, Mriganka Sarkar, Santhosh Duraisamy, H.N. Yadav, Seema Kuldeep, Soumita Bhaumik, Kunj Kumar Prajapati, Saahiba Thaleshwari, Anuj Gargya, Tamojit Santra, Sonal Amit, Rashmi Parihar, Santosh Kumar Misra, , Sai Prasad Pydi

This study shows that activating Gq-signaling in islet macrophages impairs β-cell insulin secretion via the AMPK-sphingolipid axis, revealing a new immune-endocrine communication mechanism.

bioRxiv · Oct 29, 2025 · PreprintPhysiology