Rashmi Parihar

This paper identifies myeloid Gi signaling as a weight-independent immunometabolic switch that regulates systemic insulin sensitivity through opposing cytokine programs.

This study shows that aging leads to persistent stress granules with altered RNA/RBP ratios, reduced RNA levels, and protective effects in senescent cells, which can be reversed by restoring RNA metabolism.

This study shows that activating Gq-signaling in islet macrophages impairs β-cell insulin secretion via the AMPK-sphingolipid axis, revealing a new immune-endocrine communication mechanism.