Acute Viral Infection Accelerates Neurodegeneration in a Mouse Model of ALS
Art Marzok, Jonathan Mapletoft, Imran Ahmed, Braeden Cowbrough, Daniel B. Celeste, Michael R. D’Agostino, Jann Catherine Ang, Andrew Chen, Vithushan Surendran, Yona Tugg, Hahn Li, Karena Wong, Anna Dvorkin‐Gheva, Ali Zhang, Hannah D. Stacey, , Matthew S. Miller
Acute viral infection accelerates ALS progression in SOD1G93A mice by inducing gliosis and metabolic dysregulation, which can be mitigated by anti-inflammatory or antiviral treatments.
Nature Communications · Aug 29, 2026Peer-reviewedImmunology