Author

Michael R. D’Agostino

Michael G. DeGroote Institute for Infectious Disease ResearchORCID 0000-0001-6781-9692Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Art MarzokiD· 2 shared Jann Catherine Ang· 2 shared Matthew S. MilleriD· 2 shared Sam AfkhamiiD· 2 shared Ali ZhangiD· 1 shared Andrew CheniD· 1 shared Anna Dvorkin‐GhevaiD· 1 shared Braeden CowbroughiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Art MarzokORCID

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2 papers

Recent·Most cited

ImmunologyNature CommunicationsPeer-reviewedAug 29, 2026

Acute Viral Infection Accelerates Neurodegeneration in a Mouse Model of ALS

Art Marzok, Jonathan Mapletoft, Imran Ahmed…·Matthew S. Miller

Acute viral infection accelerates ALS progression in SOD1G93A mice by inducing gliosis and metabolic dysregulation, which can be mitigated by anti-inflammatory or antiviral treatments.

1 citation

mousebulk RNA-seq

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ImmunologybioRxivPreprintMay 31, 2024

Respiratory mucosal administration of DNA aptamer nanomaterials protects against antigenically diverse SARS-CoV-2 variants

Michael R. D’Agostino, Jiuxing Li, Zijie Zhang…·Matthew S. Miller

This study shows that DNA aptamer nanomaterials can protect against diverse SARS-CoV-2 variants through respiratory mucosal administration, offering broad neutralization and superior protection compared to monoclonal antibodies.

DOI 10.1101/2024.05.31.596896

experimental assayhost-pathogen & immune response

𝕏 PostBluesky