Author

Hainan Lam

Yale University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2 Bioinformatics· 1

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 1

Frequent Co-Authors

Peggy S. MyungiD· 3 shared Ruiqi LiiD· 3 shared Yuval KlugeriD· 3 shared Chae Ho LimiD· 2 shared Eva-LaRue Barber· 2 shared Kevin A. PetersoniD· 2 shared Makoto Mark TaketoiD· 2 shared Sarah Platt· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersDevelopmental Biology

Peggy S. MyungORCID

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3 papers

Recent·Most cited

Sharp cell type boundaries emerge from coordinated morphogen signaling

Ruiqi Li, Yiqun Jiang, Sarah Platt, Tianchi Xin, Shagun Lukkad, Sarah Van, Kevin A. Peterson, Ryan R. Driskell, Jonathan Zhu, Hainan Lam, Eva-LaRue Barber, David H. Wang, Chae Ho Lim, Makoto Mark Taketo, Yuval Kluger, Peggy S. Myung

The paper shows how coordinated Wnt and Hedgehog signaling creates sharp cell-type boundaries by synchronizing cell-cycle exit and differentiation.

Genes & Development · Sep 10, 2026Peer-reviewedDevelopmental Biology

LMD: Cluster-Independent Multiscale Marker Identification in Single-cell RNA-seq Data

Ruiqi Li, Rihao Qu, Fabio Parisi, Francesco Strino, Hainan Lam, Jay S. Stanley, Xiuyuan Cheng, Peggy S. Myung, Yuval Kluger

LMD identifies localized genes in single-cell RNA-seq data to characterize cellular diversity without batch correction, outperforming existing methods.

Communications Biology · Jul 16, 2025Peer-reviewedBioinformatics

Sharp cell-type boundaries emerge from temporal coordination between morphogen signals

Ruiqi Li, Yiqun Jiang, Sarah Platt, Tianchi Xin, Ryan Driskell, Kevin A. Peterson, Sarah Van, Hainan Lam, Shagun Lukkad, Eva-LaRue Barber, Chae Ho Lim, Makoto Mark Taketo, Yuval Kluger, Peggy S. Myung

The paper shows that coordinated timing between Wnt and Hedgehog signaling generates sharp cell-type boundaries during hair follicle development.

bioRxiv · Jun 29, 2025 · PreprintDevelopmental Biology