Rihao Qu

This study identifies nerve-associated macrophages (NAMs) as regulators of adipose homeostasis and inflammation during aging, showing their depletion accelerates inflammaging and impairs lipolysis.

LMD identifies localized genes in single-cell RNA-seq data to characterize cellular diversity without batch correction, outperforming existing methods.

This study uses single-nucleus multiome sequencing to identify HIV-associated transcriptional and epigenetic changes in brain regions of individuals with HIV, revealing altered glial cell states and pro-inflammatory signaling.

This study shows IL-4 promotes B cell activation by upregulating cholesterol synthesis, which is essential for ER expansion, cell cycle progression, and proliferation during influenza infection.

GeneTrajectory infers gene trajectories instead of cell trajectories to uncover progressive gene dynamics in biological processes.

This study profiles gene and miRNA expression in mouse pituitaries across postnatal ages to identify sex-biased gene regulation and cell-type proportion differences during development.