Author

Hainin Lin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:software / tool· 1

Frequent Co-Authors

Mihir MetkariD· 2 shared Adriana K. Jones· 1 shared Alicia A. BicknelliD· 1 shared Angie Kim· 1 shared Brent M. ZnoskoiD· 1 shared David H. MathewsiD· 1 shared Elizabeth A. JolleyiD· 1 shared Elzbieta Kierzek· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBioinformatics

Mihir MetkarORCID

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2 papers

Recent·Most cited

RNA Folding Nearest Neighbor Parameters Including the Modification 1-Methyl-Pseudouridine

Elzbieta Kierzek, Thandolwethu S. Shabangu, Olivia M. Hiltke, Megan Miaro, Sebastian J. Arteaga, Brent M. Znosko, Elizabeth A. Jolley, Philip C. Bevilacqua, John SantaLucia, Holly A. SantaLucia, Hainin Lin, Mihir Metkar, Sharon Aviran, Marta Soszynska-Jozwiak, Ryszard Kierzek, David H. Mathews

This paper develops new RNA folding nearest neighbor parameters for sequences containing 1-methyl-pseudouridine, showing it stabilizes RNA folding and improves tRNA ensemble modeling.

bioRxiv · Apr 11, 2026 · PreprintBioinformatics

mRNAfold: Co-optimization of Global Stability, Local Structure, and Codon Choice via Suboptimal Folding

Max Ward, Mary O.G. Richardson, Hainin Lin, Michae Stamm, Kathryn Wright, Angie Kim, Alicia A. Bicknell, Nabeel Ahmed, Adriana K. Jones, J. Wade Davis, Mihir Metkar

mRNAfold improves mRNA design by co-optimizing stability, local structure, and codon choice, showing better in-solution stability and complex effects on protein production.

bioRxiv · Jan 26, 2026 · PreprintBioinformatics