Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.
Filip Mihalič, Caroline Benz, Eszter Kassa, Richard Lindqvist, Leandro Simonetti, Raviteja Inturi, Hanna Aronsson, Eva Andersson, N. Celestine, Norman E. Davey, Anna K. Överby, Per Jemth, Ylva Ivarsson
The paper identifies SARS-CoV-2 protein domains that interact with human peptides and discovers antiviral peptides targeting Nsp9 and Nsp16.
Nature Communications · Sep 13, 2023Peer-reviewedMolecular Biology