Anna K. Överby

Cryo-ET of Langat virus-infected cells shows replication organelle size set by a membrane coat plus RNA pressure, with virion budding and maturation occurring beside the organelles.

This study investigates POWV lineage II pathogenesis in mice, finding that distinct disease phenotypes arise from genetic variations beyond nonsynonymous mutations.

This study investigates how structural proteins of TBEV influence viral tropism by comparing a chimeric virus with low-pathogenic LGTV and TBEV using structural and imaging analyses.

This study uses phage-based deep mutational scanning to identify binding determinants of short linear motifs between human and SARS-CoV-2 proteins, refining motifs and identifying affinity-enhancing mutations.

This study identifies ACBD3 as a host factor recruited by flavivirus NS4B to modify ER-Golgi trafficking for virion release.

The paper identifies SARS-CoV-2 protein domains that interact with human peptides and discovers antiviral peptides targeting Nsp9 and Nsp16.

The paper develops an MR-based brain template and atlas for optical imaging techniques, enabling anatomical mapping of fluorescent signals in cleared mouse brains.