Effects of electroconvulsive shock on the function, circuitry, and transcriptome of dentate gyrus granule neurons
Adrienne N. Santiago, Julia Castello Saval, Phi Nguyen, Hannah M. Chung, Shaharia Khan, Victor M. Luna, René Hen, Wei-li Chang
This study shows ECS-induced neurogenesis is necessary for antidepressant effects and identifies transcriptomic changes in granule neurons.
Neuropsychopharmacology · Feb 4, 2026Peer-reviewedNeuroscience