Author

Hannah M. Knox

Salk Institute for Biological Studies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Immunology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alexandra C. NewtoniD· 1 shared Anna-Maria GlobigiD· 1 shared Bryan McDonaldiD· 1 shared H. Kay ChungiD· 1 shared Hubert TsengiD· 1 shared Jesse Furgiuele· 1 shared Johnny Koo· 1 shared Majid GhassemianiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Alexandra C. NewtonORCID

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1 paper

Recent·Most cited

Different signaling interpretations by PKC eta and theta control T cell function and exhaustion

Thomas H. Mann, Hannah M. Knox, Shixin Ma, Jesse Furgiuele, Anna-Maria Globig, Michael A. LaPorta, H. Kay Chung, Bryan McDonald, Majid Ghassemian, Steven Zhao, Hubert Tseng, Yagmur Farsakoglu, Victoria Tripple, Johnny Koo, Alexandra C. Newton, Susan M. Kaech

This study shows PKC theta sustains T cell function while PKC eta drives terminal exhaustion, with distinct downstream cascades and therapeutic implications for cancer immunotherapy.

bioRxiv · Sep 26, 2024 · PreprintImmunology