Author

Haocheng Yang

University of Hong Kong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Approach:statistical model· 1 Assay:structural biology· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Jason W.H. WongiD· 3 shared Jayne A. BarbouriD· 2 shared Abigail J Dennis· 1 shared Adriana LoriiD· 1 shared Alisa M. GoldsteiniD· 1 shared Amy HutchinsoniD· 1 shared Belynda D. HicksiD· 1 shared Douglas R. StewartiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersBiochemistry

Jason W.H. WongORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mechanistic insights into chromatin modulation by the orphan remodeler ATRX

Suling Duan, Tsz-Fung Wong, Xian Yang, Haocheng Yang, Huimin Xi, Yanxiang Zhao, Zhong‐Ping Yao, Yuanliang Zhai, 廖健佑, Jason W.H. Wong, Tao Ni, Keda Zhou, Yang Liu

This study reveals how ATRX modulates chromatin by unwrapping nucleosomal DNA through a unique 'pin-like' structure and other features, proposing a 'climbing' mechanism for DNA translocation.

Molecular Cell · Oct 1, 2026Peer-reviewedBiochemistry

Disruption of CTCF binding by germline non-coding variants in CDKN2B suppress CDKN2A expression and predispose to melanoma

Jessica L. Scales, Jayne A. Barbour, Alisa M. Goldstein, Rebecca Hennessey, Mai Xu, Abigail J Dennis, Sophie Papiernik, Jung Kim, Sudipto Das, Haocheng Yang, S. Chul Kwon, Kornelia Gladysz, Rohit Thakur, Joshuah Yon, Linh Bui-Raborn, , Xiaohong R Yang

The paper identifies non-coding variants in CDKN2B that disrupt CTCF binding, reduce CDKN2A expression, and increase melanoma risk in families.

medRxiv · Jun 2, 2026 · PreprintGenetic & Genomic Medicine

Global and local redistribution of somatic mutations enable the prediction of functional XPD mutations in bladder cancer

Jayne A. Barbour, Tong Ou, Haocheng Yang, Fang Hu, Noel C. Yue, Xiaoqiang Zhu, Michelle W. Wong‐Brown, Yuen T. Wong, Nikola A. Bowden, Song Wu, Jason W.H. Wong

The paper identifies how XPD mutations alter somatic mutation patterns in bladder cancer and develops a machine-learning model to predict pathogenic XPD mutations with 100% accuracy in an independent cohort.

Cell Genomics · Aug 1, 2024Peer-reviewedMolecular Biology