Author

Harshini Kelam

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alena KlochkovaiD· 2 shared Andrew E. VaughaniD· 2 shared Diana M Abraham· 2 shared Evelyn A. Martinez· 2 shared Joanna WongiD· 2 shared Madeline SinghiD· 2 shared Meryl MendozaiD· 2 shared Nicolas P. HolcombiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Alena KlochkovaORCID

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Author profile →

2 papers

Recent·Most cited

Influenza-induced tuft cell expansion alters ILC-mediated inflammation

Maria Elena Gentile, Michael M. Maiden, Madeline Singh, Evelyn A. Martinez, Harshini Kelam, Nicolas P. Holcomb, Joanna Wong, Meryl Mendoza, Diana M Abraham, Alena Klochkova, Sara Kass-Gergi, Andrew E. Vaughan

This study shows that influenza-induced tuft cell expansion interacts with ILC2s to regulate inflammation, with tuft cell deficiency altering ILC subsets and inflammatory responses.

bioRxiv · May 12, 2026 · PreprintMolecular Biology

Dysplastic Epithelial Repair Propagates Chronic Pathology Through the Paracrine Transformation of Pulmonary Fibroblasts

Nicolas P. Holcomb, Ronel Z. Samuel, Alena Klochkova, Joanna Wong, Sara Kass-Gergi, Meryl Mendoza, Michael M Maideen, Evelyn A. Martinez, Diana M Abraham, Madeline Singh, Harshini Kelam, Jarod A. Zepp, Andrew E. Vaughan

The paper shows dysplastic basal cells induce an inflammatory fibroblast phenotype through IL-1 secretion, promoting chronic inflammation and fibrosis.

bioRxiv · Apr 5, 2026 · PreprintCell Biology