CRISPR gene and transcriptome engineering (CRISPRgate) improves loss-of-function genetic screening approaches
Jannis Stadager, Chiara Bernardini, Laura Hartmann, Henrik May, Jessica Wiepcke, Monika Kuban, Zeynab Najafova, Steven A. Johnsen, Stefan Legewie, Franziska R. Traube, Julian Jude, Philipp Rathert
CRISPRgate improves loss-of-function screening by combining CRISPRko and CRISPRi to enhance gene repression and reduce noise in genetic studies.
bioRxiv · May 14, 2024Biochemistry