Author

Hester Heimans

Oncode Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Ben MorrisiD· 1 shared Cor LieftinkiD· 1 shared Daimy van der Ven· 1 shared João M. Fernandes NetoiD· 1 shared Katarzyna JastrzebskiiD· 1 shared Lenno KrenningiD· 1 shared Matheus Dias· 1 shared René BernardsiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Ben MorrisORCID

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1 paper

Recent·Most cited

Performance of large scale pooled CRISPR screens is dependent on Cas9 expression levels

João M. Fernandes Neto, Cor Lieftink, Katarzyna Jastrzebski, Lenno Krenning, Matheus Dias, Ben Morris, Daimy van der Ven, Hester Heimans, René H. Medema, René Bernards, Roderick L. Beijersbergen

This study shows that Cas9 expression levels significantly affect the efficiency and speed of large-scale pooled CRISPR screens, with higher Cas9 expression improving performance.

bioRxiv · Jul 13, 2021 · PreprintGenomics