Author

Hilal Ahmad Mir

Columbia University Irving Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

Arunan Palanimuthu· 1 shared Carlos SerraiD· 1 shared Christopher L. CioffiiD· 1 shared Emily Sun· 1 shared Gaddam Mahesh· 1 shared Konstantin E. PetrukhiniD· 1 shared Neel H. ShahiD· 1 shared Neoklis MakridesiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperPharmacology & Toxicology

Arunan Palanimuthu

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2 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintMar 23, 2026

Loss of Lamp2a-dependent chaperone-mediated autophagy drives dry AMD-like retinal pathology in mice and is rescued by BK channel activation

Hilal Ahmad Mir, Gaddam Mahesh, Arunan Palanimuthu…·Konstantin E. Petrukhin

This study shows that loss of CMA in mice leads to AMD-like retinal pathology, which is reversed by activating BK channels with GLA-1-1.

DOI 10.64898/2026.03.19.712761

mouseexperimental assay

𝕏 PostBluesky

PathologybioRxivPreprintJan 28, 2025

Allosteric inhibition rescues hydrocephalus caused by catalytically inactive Shp2

Neoklis Makrides, Emily Sun, Hilal Ahmad Mir…·Xin Zhang

This study shows that a catalytically inactive Shp2 mutation causes hydrocephalus by altering conformation, which can be rescued by allosteric inhibition.

3 citations

mouseexperimental assay

𝕏 PostBluesky