Author

Himani Patel

Massachusetts General Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:simulation· 1 Approach:statistical model· 1

Frequent Co-Authors

Benedikt R. Dürr· 2 shared Brian B. LiauiD· 2 shared Harrison Byron ChongiD· 2 shared Junbing ZhangiD· 2 shared Liron Bar‐PelediD· 2 shared Marianne Richter· 2 shared Mariko TakahashiiD· 2 shared Michael S. LawrenceiD· 2 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSystems Biology

Benedikt R. Dürr

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

DrugMap: A quantitative pan-cancer analysis of cysteine ligandability

Mariko Takahashi, Harrison Byron Chong, Siwen Zhang, Tzu-yi Yang, Matthew J. Lazarov, Stefan Andrew Harry, Michelle Maynard, Brendan J. Hilbert, Ryan D. White, Heather E. Murrey, Chih‐Chiang Tsou, Kira Vordermark, Jonathan Assaad, Magdy Gohar, Benedikt R. Dürr, , Liron Bar‐Peled

DrugMap quantitatively analyzes cysteine ligandability across 416 cancer cell lines, revealing redox state, conformational changes, and mutations as drivers of variability, and identifies covalent inhibitors targeting NFκB1 and SOX10.

Cell · Apr 22, 2024Peer-reviewedSystems Biology

Identification of chemotherapy targets reveals a nucleus-to-mitochondria ROS sensing pathway

Junbing Zhang, Claire M. Simpson, Jacqueline Berner, Harrison Byron Chong, Jiafeng Fang, Zehra Ordulu, Tommy Weiss‐Sadan, Anthony P. Possemato, Stefan Andrew Harry, Mariko Takahashi, Tzu-yi Yang, Marianne Richter, Himani Patel, Abby E. Smith, Alexander Daniel Carlin, , Liron Bar‐Peled

The paper identifies a nucleus-to-mitochondria ROS sensing pathway involving CHK1 and SSBP1 that mediates resistance to platinum-based chemotherapies in ovarian cancers.

bioRxiv · Mar 11, 2023 · PreprintMolecular Biology

3D viscoelastic drag forces contribute to cell shape changes during organogenesis in the zebrafish embryo

Paula C. Sanematsu, Gonca Erdemci-Tandogan, Himani Patel, Emma M. Retzlaff, Jeffrey D. Amack, M. Lisa Manning

This paper investigates how 3D viscoelastic drag forces from tailbud tissue drive cell shape changes in the zebrafish embryo's Kupffer's Vesicle during organogenesis.

Cells and Development · Jul 14, 2021Peer-reviewedDevelopmental Biology