Jeffrey D. Amack

Size-Modulated Mesoderm-Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

This study uses micropatterned cardioids to investigate mesoderm-endoderm interactions in heart development, finding that pattern size affects cavity formation and signaling.

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

This study shows Fhod3 is essential for maintaining myofibril stability during skeletal muscle growth in zebrafish but not for initial myofibril assembly.

Dynamical forces drive cell and organ morphology changes during embryonic development

The paper shows dynamic forces from tissue movements shape the Kupffers vesicle in zebrafish embryos, confirmed by modeling and laser ablation experiments.

3D viscoelastic drag forces contribute to cell shape changes during organogenesis in the zebrafish embryo

This paper investigates how 3D viscoelastic drag forces from tailbud tissue drive cell shape changes in the zebrafish embryo's Kupffer's Vesicle during organogenesis.

An unconventional myosin, myosin 1d regulates Kupffer’s vesicle morphogenesis and laterality

The paper shows myosin 1d is essential for establishing left-right asymmetry in zebrafish through actin-myosin driven chirality.

Asymmetric cell volume changes regulate epithelial morphogenesis in zebrafish Kupffers vesicle

The paper identifies asymmetric cell volume changes in zebrafish Kupffer's vesicle that drive cell shape changes during epithelial morphogenesis, independent of lumen expansion.