Author

Hongyu Wang

The University of Texas Health Science Center at Houston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Approach:contrastive learning· 1 Approach:deep learning· 1

Frequent Co-Authors

Haotian DangiD· 2 shared Lei YouiD· 2 shared Xiaobo zhou· 2 shared Xiaowei Wang· 2 shared Daiwen CheniD· 1 shared Dongmei JiangiD· 1 shared Eduardo da Matta· 1 shared Fei Luo· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBioengineering

Haotian DangORCID

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Author profile →

4 papers

Recent·Most cited

AC-Diff: Anatomy-Contrast Disentangled Diffusion for Multi-Vendor Liver MRI Harmonization

Hansen Feng, Haotian Dang, Lei You, Hongyu Wang, Xiaobo zhou

AC-Diff improves liver MRI harmonization by separating anatomy from contrast, achieving better segmentation results.

bioRxiv · Sep 29, 2026 · PreprintBioengineering

Synchronized Latency Reversal and Immune Clearance by a Multifunctional Fusion Protein Enables HIV-1 Reservoir Reduction

Fei Luo, Yinghui Cao, N K Liu, Xiaowei Wang, Wenjia Hu, Yajun Yan, Xiaoqing Xie, Dongmei Jiang, Yangyang Xu, Jun Wang, Hongyu Wang, Zhenyang Yu, Peng Qian, Shicheng Wan, Zhida Liu, , Liang Cheng

This paper develops a fusion protein that reactivates HIV-1 latency and enhances immune clearance, reducing viral reservoirs in HIV-infected individuals and humanized mice.

Molecular Therapy · Jul 29, 2026Peer-reviewedImmunology

Anatomy-Guided 3D Graph Networks for Couinaud Segmentation in Tumor Affected Livers

Lei You, Haotian Dang, Hongyu Wang, Eduardo da Matta, Xiaobo zhou

This paper introduces a two-stage framework combining 3D UNet and 3D GCN for accurate Couinaud segmentation in tumor-affected livers, achieving a mean Dice score of 0.828 on blind testing.

bioRxiv · Jun 29, 2026 · PreprintBioinformatics

ORP2 regulates free cholesterol accumulation in hepatocytes during MASH

Jin Wu, Yudi Zhao, Liwen Qiu, Qiaoli Chen, Xiaowei Wang, Jingwen Gu, Yan Liang, Yingjie Zhang, Hongyu Wang, Yang Liu, Xiaoqin Wu, Daiwen Chen, Feng‐Jung Chen, Mingming Gao, Hongyuan Yang

This study shows that ORP2 prevents free cholesterol accumulation in mouse liver, and its absence leads to severe MASH with cholesterol crystals.

Hepatology Communications · Jul 14, 2025Peer-reviewedCell Biology