Author

HuiXing Chen

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Approach:statistical model· 3 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Chencheng YaoiD· 3 shared Liangyu ZhaoiD· 3 shared Ruhui TianiD· 3 shared Zhi ZhouiD· 3 shared ChenChen WangiD· 2 shared Jiaqiang LuoiD· 2 shared Jie SuniD· 2 shared Na LiiD· 2 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersDevelopmental Biology

Chencheng YaoORCID

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3 papers

Recent·Most cited

The XPF-like domain in SHOC1 required for homologous recombination and safeguarding autosome from meiotic silencing of unsynapsed chromatin

Yuxiang Zhang, Qian Sun, Zhiyong Ji, Ren Mo, Yuchuan Zhou, Jingpeng Zhao, Shuai Xu, Na Li, Yifan Sun, Haowei Bai, Erlei Zhi, Sha Han, Huixing Chen, Jing Zhang, Dewei Qian, , Chencheng Yao

The paper identifies a missense variant in the XPF-like domain of SHOC1 that disrupts meiotic recombination and causes meiotic arrest by impairing DNA repair and chromatin structure.

bioRxiv · May 28, 2025 · PreprintDevelopmental Biology

Low XIST expression in Sertoli cells of Klinefelter syndrome patients caused the high susceptibility of these cells to an extra X chromosome

Liangyu Zhao, Peng Li, Chencheng Yao, Xiaoyu Xing, Chao Yang, Jiaqiang Luo, Zhiyong Ji, Ruhui Tian, HuiXing Chen, Zijue Zhu, ZhiWen Deng, Na Li, Jing Fang, Jie Sun, ChenChen Wang, , Zheng Li

bioRxiv · Aug 26, 2020 · PreprintGenomics

Single-cell atlas of human developing and azoospermia patients' testicles reveals the roadmap and defects in somatic microenvironment

Liangyu Zhao, Chencheng Yao, Xiaoyu Xing, Tao Jing, Peng Li, Zijue Zhu, Chao Yang, Jing Zhai, Ruhui Tian, HuiXing Chen, Jiaqiang Luo, Nachuan Liu, ZhiWen Deng, Xiaohan Lin, Na Li, , Zheng Li

This study creates a single-cell atlas of human testicular development and NOA patients, revealing Sertoli cell maturation defects and potential therapeutic strategies.

bioRxiv · May 7, 2020 · PreprintDevelopmental Biology