Author

I. B. Hilton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:CRISPR screen· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Mahata· 2 shared D. A. Brenner· 2 shared A. Cabrera· 1 shared A. K. Parthasarathy· 1 shared A. R. DiNardo· 1 shared Abhimanyu· 1 shared D. Reed· 1 shared G. Bedford· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

B. Mahata

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Author profile →

2 papers

Recent·Most cited

Persistent tailoring of MSC activation through genetic priming

M. A. Beauregard, G. C. Bedford, D. A. Brenner, L. D. Sanchez Solis, T. Nishiguchi, Abhimanyu, S. Carrero Longlax, B. Mahata, O. Veiseh, P. L. Wenzel, A. R. DiNardo, I. B. Hilton, M. R. Diehl

This paper introduces a genetic priming method using IRF1 to sustainably enhance MSC potency and suppress immunogenicity compared to biochemical priming.

bioRxiv · Feb 1, 2024Bioengineering

Compact engineered human mechanosensitive transactivation modules enable potent and versatile synthetic transcriptional control

B. Mahata, A. Cabrera, D. A. Brenner, R. S. Guerra-Resendez, J. Li, J. Goell, K. Wang, Y. Guo, M. Escobar, A. K. Parthasarathy, H. Szadowski, G. Bedford, D. Reed, I. B. Hilton

This paper develops compact human mechanosensitive TADs for synthetic transcriptional control, showing they are potent, versatile, and well-tolerated in primary cells.

bioRxiv · Mar 21, 2022Bioengineering