Author

I. Cho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

N. Ali· 3 shared P. P. Lui· 3 shared B. Xie· 2 shared H. Aziz· 2 shared J. Z. Xu· 2 shared P.-H. Tsai· 2 shared A. E. Denton· 1 shared B. Ma· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

N. Ali

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Jagged-1+ Tregs Mediate Lymphatic Remodeling in Tumour-Draining Lymph Nodes

J. Z. Xu, P. P. Lui, P.-H. Tsai, H. Aziz, B. Xie, I. Cho, M. Terranova-Barberio, C. Z. Li, K. Stoker, H. Yu, A. E. Denton, T. Lawrence, S. N. Karagiannis, N. Ali

This study shows that Jag1-expressing regulatory T cells (Tregs) in tumor-draining lymph nodes (tdLNs) are essential for lymphatic remodeling and niche formation during melanoma progression.

bioRxiv · Jun 10, 2024 · PreprintImmunology

Early life regulatory T cells modulate PPAR-gamma dependent skin pigmentation

I. Cho, J. Z. Xu, H. Aziz, P. P. Lui, B. Xie, P.-H. Tsai, H.-Y. Jeon, J. Choi, S. Ali, N. Ali

The paper shows that early life regulatory T cells (ETregs) regulate PPAR-gamma signaling in hair follicles, which is essential for melanocyte stem cell-mediated skin pigmentation.

bioRxiv · Oct 17, 2023Immunology

Chitinase 3-like-1 (CHI3L1) in the Pathogenesis of Epidermal Growth Factor Receptor Mutant Non-Small Cell Lung Cancer

S. Kamle, B. Ma, G. Schor, M. Bailey, B. Pham, I. Cho, H. Khan, C. Azzoli, M. Hofstetter, C.-M. Lee, R. Herbst, K. Politi, C. G. Lee, J. A. Elias

This study shows CHI3L1 is induced by EGFR activation in NSCLC and promotes EGFR signaling, with anti-CHI3L1 antibodies reversing TKI resistance and inhibiting metastasis.

bioRxiv · Sep 21, 2023Cancer Biology

Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation induced tissue damage

E. Rognoni, G. Goss, T. Hiratsuka, K. I. Kober, P. P. Lui, V. S. Tsang, N. Hawkshaw, S. M. Pilkington, K. Sipilä, I. Cho, N. Ali, L. E. Rhodes, F. M. Watt

This study investigates the role of fibroblast lineages and immune cells in dermal repair after UV radiation damage, finding that T cells support fibroblast survival and that COX-2 inhibition prevents fibroblast depletion.

bioRxiv · Jun 8, 2021Cell Biology