Author

I. Grin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

S. Wagner· 3 shared E. Bohn· 2 shared A. Boudrioua· 1 shared A. Flieger· 1 shared A. Kohler· 1 shared A. Meir· 1 shared A. Naini· 1 shared A. Poso· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersMicrobiology

S. Wagner

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3 papers

Recent·Most cited

Discovery of a synthetic small molecule targeting the central regulator of Salmonella pathogenicity

A. Boudrioua, J. D. Joiner, I. Grin, T. Kronenberger, V. S. Korotkov, W. Steinchen, A. Kohler, S. Schminke, J.-C. Schulte, M. Pietsch, A. Naini, S. Kalverkamp, S.-K. Hotop, T. Coyle, C. Piselli, , S. Wagner

The paper identifies a synthetic small molecule, C26, that inhibits HilD, a key regulator of Salmonella secretion systems, thereby preventing bacterial invasion of host cells.

bioRxiv · Apr 29, 2024 · PreprintMicrobiology

The T4bSS of Legionella features a two-step secretion pathway with an inner membrane intermediate for secretion of transmembrane effectors

S. Wagner, S. Malmsheimer, I. Grin, E. Bohn, M. Franz-Wachtel, B. Macek, T. Sahr, F. Smollich, D. Chetrit, A. Meir, C. Roy, C. Buchrieser

This study investigates the secretion mechanism of transmembrane effector proteins by Legionella T4bSS, revealing a two-step process involving an inner membrane intermediate.

bioRxiv · Mar 14, 2024 · PreprintMicrobiology

A NanoLuc luciferase-based assay enabling the real-time analysis of protein secretion and injection by bacterial type III secretion systems

S. Westerhausen, M. Nowak, C. E. Torres-Vargas, U. Bilitewski, E. Bohn, I. Grin, S. Wagner

This paper develops a NanoLuc luciferase-based assay to quantitatively monitor bacterial type III secretion and injection of effector proteins into host cells.

bioRxiv · Aug 25, 2019Microbiology