M. D. Rosenblum

Tertiary Lymphoid Structures Sustain Cutaneous B cell Activity in Hidradenitis Suppurativa

The paper identifies tertiary lymphoid structures in HS lesions and shows B cell maturation and interactions with T cells and stroma.

Single-cell analyses identify circulating anti-tumor CD8 T cells and markers for their enrichment

The paper identifies circulating anti-tumor CD8 T cells using single-cell RNA sequencing and TCR sequencing, and develops marker panels for their detection in mice and melanoma patients.

Developing human fetal skin demonstrates a unique lymphocyte signature

The paper identifies a unique lymphocyte signature in human fetal skin using mass and flow cytometry, highlighting memory-like features and IFNγ production in fetal T cells.

A novel humanized mouse model to study the function of human cutaneous memory T cells in vivo in human skin

This study develops a humanized mouse model to study human cutaneous memory T cells in vivo, showing their functional profiles and responses to pathogens.

Integrin αvβ8 on T cells is responsible for suppression of anti-tumor immunity in multiple syngeneic models and is a promising target for tumor immunotherapy

This study shows that blocking integrin αvβ8 on T cells enhances anti-tumor immunity in multiple syngeneic models and is effective even when tumor cells do not express the integrin.

Human CD4+CD103+ cutaneous resident memory T cells are found in the circulation of healthy subjects

The paper identifies human CD4+CD103+ cutaneous resident memory T cells in circulation and shows they can migrate to distant skin sites.