Author

I. Liachko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:metagenomics· 4 Research Focus:clustering· 3 Assay:long-read sequencing· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

M. O. Press· 3 shared K. Panke-Buisse· 2 shared S. T. Sullivan· 2 shared A. Damerum· 1 shared A. Korobeynikov· 1 shared A. M. Phillippy· 1 shared A. Oladeinde· 1 shared A. S. Bhatt· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersMicrobiology

M. O. Press

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Author profile →

6 papers

Recent·Most cited

Highly accurate metagenome-assembled genomes from human gut microbiota using long-read assembly, binning, and consolidation methods

D. M. Portik, X. Feng, G. Benoit, D. J. Nasko, B. Auch, S. J. Bryson, R. Cano, M. Carlin, A. Damerum, B. Farthing, J. R. Grove, M. Islam, K. W. Langford, I. Liachko, K. Locken, , J. E. Wilkinson

This study improves metagenome-assembled genomes from human gut microbiota using long-read sequencing and novel assembly methods, yielding more high-quality MAGs and uncovering uncultured diversity.

bioRxiv · May 10, 2024 · PreprintMicrobiology

Analysis and culturing of the prototypic crAssphage reveals a phage-plasmid lifestyle

D. T. Schmidtke, A. S. Hickey, I. Liachko, G. J. Sherlock, A. S. Bhatt

This study characterizes the crAssphage lifestyle as a phage-plasmid, demonstrating its persistence in the gut microbiome without causing host lysis or chromosomal integration.

bioRxiv · Mar 20, 2024 · PreprintMicrobiology

Generation of lineage-resolved complete metagenome-assembled genomes by precision phasing

D. M. Bickhart, M. Kolmogorov, E. Tseng, D. Portik, A. Korobeynikov, I. Tolstoganov, G. Uritskiy, I. Liachko, S. T. Sullivan, S. B. Shin, A. Zorea, V. P. Andreu, K. Panke-Buisse, M. H. Medema, I. Mizrahi, , T. P. Smith

The paper generates lineage-resolved complete MAGs using HiFi reads from sheep fecal samples, achieving high-resolution deconvolution of microbial communities.

bioRxiv · May 4, 2021 · PreprintMicrobiology

Litter commensal bacteria can limit the horizontal gene transfer of antimicrobial resistance to Salmonella in chickens

A. Oladeinde, Z. Abdo, B. Zwirzitz, R. Woyda, S. M. Lakin, M. O. Press, N. A. Cox, J. C. Thomas, T. P. Looft, M. J. Rothrock, G. Zock, J. Plumblee Lawrence, D. Cudnik, C. Ritz, S. E. Aggrey, , C. Wiersma

This study shows that commensal bacteria in reused chicken litter reduce horizontal gene transfer of antimicrobial resistance plasmids to Salmonella.

bioRxiv · Apr 2, 2021Microbiology

Assignment of virus and antimicrobial resistance genes to microbial hosts in a complex microbial community by combined long-read assembly and proximity ligation

D. Bickhart, M. Watson, S. Koren, K. Panke-Buisse, L. M. Cersosimo, M. O. Press, C. P. Van Tassell, J. A. S. Van Kessel, B. J. Haley, S. W. Kim, C. Heiner, G. Suen, K. Bakshy, I. Liachko, S. T. Sullivan, , T. P. L. Smith

This study uses long-read sequencing and proximity ligation to improve the characterization of a complex cattle rumen microbial community, identifying novel viral-host associations and more antimicrobial resistance genes.

bioRxiv · Dec 9, 2018Microbiology

Linking the Resistome and Plasmidome to the Microbiome

T. Stalder, M. O. Press, S. Sullivan, I. Liachko, E. M. Top

This study uses Hi-C to identify the in situ host range of antibiotic resistance genes, plasmids, and integrons in wastewater, revealing their associations with host genomes.

bioRxiv · Dec 3, 2018Microbiology