Author

I. Sahin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. S. Kocagoz· 2 shared B. Yurtsever· 2 shared C. Hemsinlioglu· 2 shared C. Tastan· 2 shared D. Cakirsoy· 2 shared D. Dilek Kancagi· 2 shared D. Telci· 2 shared E. Ovali· 2 shared

Activity by Year

2020-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

A. S. Kocagoz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Gamma-irradiated SARS-CoV-2 vaccine candidate, OZG-38.61.3, confers protection from SARS-CoV-2 challenge in human ACEII-transgenic mice

R. D. Turan, C. Tastan, D. Dilek Kancagi, B. Yurtsever, G. Sir Karakus, S. Ozer, S. Abanuz, D. Cakirsoy, G. Tumentemur, S. Demir, U. Seyis, R. Kuzay, M. Elek, M. E. Kocaoglu, G. Ertop, , E. Ovali

This paper describes an inactivated SARS-CoV-2 vaccine candidate, OZG-38.61.3, that provides protection in human ACE2-transgenic mice through gamma irradiation and intradermal administration.

bioRxiv · Oct 28, 2020Immunology

Preliminary report of preclinical efficacy and safety analysis of gamma-irradiated inactivated SARS-CoV-2 vaccine candidates, SK-01 version 1 and OZG-3861 version 1

G. SIR KARAKUS, C. Tastan, D. Dilek Kancagi, B. Yurtsever, G. Tumentemur, S. Demir, R. D. Turan, S. Abanuz, D. Cakirsoy, U. Seyis, S. Ozer, O. Elibol, M. Elek, G. Ertop, S. Arbak, , E. Ovali

This study evaluates the safety and immunogenicity of two gamma-irradiated inactivated SARS-CoV-2 vaccines in mice, showing significant antibody and T cell responses without antibody-dependent enhancement.

bioRxiv · Sep 4, 2020 · PreprintImmunology

Natural Killer cell activation, reduced ACE2, TMPRSS2, cytokines G-CSF, M-CSF and SARS-CoV-2-S pseudovirus infectivity by MEK inhibitor treatment of human cells

L. Zhou, K. Huntington, S. Zhang, L. Carlsen, E.-Y. So, C. Parker, I. Sahin, H. Safran, S. Kamle, C.-M. Lee, C.-G. Lee, J. A. Elias, K. S. Campbell, M. T. Naik, W. J. Atwood, , W. El-Deiry

This study shows MEK inhibitors reduce ACE2 and inflammatory cytokines, enhance NK cell activity, and block SARS-CoV-2 pseudovirus infection in human cells.

bioRxiv · Aug 2, 2020 · PreprintCell Biology