I. Sanders

Circadian desynchronization desensitizes insulin-producing cells to cytokine-mediated transcriptomic remodeling and cell death: a novel beta-cell anti-apoptotic response to inflammation

This study shows that circadian desynchronization protects insulin-producing cells from cytokine-induced transcriptomic changes and cell death by modulating NF-κB signaling and clock gene regulation.

Cachexia and fibrosis are costs of chronic IL-1R-mediated disease tolerance in T. gondii infection

This study shows that IL-1R signaling protects mice from acute T. gondii infection but leads to chronic cachexia and fibrosis when sustained.