GLYCOLYTIC REPROGRAMMING FUELS MYELOID CELL-DRIVEN HYPERCOAGULABILITY
A. M. Rehill, G. Leon, S. McCluskey, I. Schoen, Y. Hernandez-Santana, S. L. Annett, P. Klavina, T. Robson, A. M. Curtis, T. Renne, S. Hussey, J. S. O'Donnell, P. T. Walsh, R. J. Preston
This study shows inflammation-induced glycolytic reprogramming in myeloid cells drives hypercoagulability and antifibrinolytic activity, with potential therapeutic implications.
bioRxiv · Apr 20, 2023Immunology