Author

I. Sethi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:flow cytometry· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

I. W. Babcock· 3 shared L. A. Sibley· 3 shared M. A. Kovacs· 3 shared M. N. Cowan· 3 shared S. A. Labuzan· 3 shared T. H. Harris· 3 shared K. Still· 2 shared S. J. Batista· 2 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

I. W. Babcock

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Caspase-1 in Cx3cr1-expressing cells drives an IL-18-dependent T cell response that promotes parasite control during acute T. gondii infection

I. W. Babcock, L. A. Sibley, S. A. Labuzan, M. N. Cowan, I. Sethi, S. Alemu, M. A. Kovacs, J. R. Lukens, T. H. Harris

This study shows that caspase-1 in Cx3cr1-expressing cells drives IL-18 release, enhancing CD4+ T cell IFN-γ production and parasite control during acute T. gondii infection.

bioRxiv · Jan 29, 2024 · PreprintImmunology

Microglial STAT1-sufficiency is required for resistance to toxoplasmic encephalitis

M. N. Cowan, M. A. Kovacs, I. Sethi, I. W. Babcock, K. Still, S. J. Batista, C. A. O'Brien, J. A. Thompson, L. A. Sibley, S. A. Labuzan, T. H. Harris

This study shows that microglial STAT1 is essential for controlling T. gondii infection and preventing toxoplasmic encephalitis by regulating microglial activation and anti-parasitic functions.

bioRxiv · Jun 6, 2022Immunology

Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain

M. A. Kovacs, M. N. Cowan, I. W. Babcock, L. A. Sibley, K. Still, S. J. Batista, S. A. Labuzan, I. Sethi, T. H. Harris

bioRxiv · Jun 2, 2022Immunology