Author

J. R. Lukens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. C. Debski· 1 shared A. E. Ross· 1 shared A. G. Ball· 1 shared A. W. L. Kinman· 1 shared B. D. Groff· 1 shared C. A. O'Brien· 1 shared C. M. Gorick· 1 shared D. G. Fisher· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioengineering

A. C. Debski

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Focused Ultrasound Blood-Brain Barrier Opening Arrests the Growth and Formation of Cerebral Cavernous Malformations

D. G. Fisher, K. A. Sharifi, I. M. Shah, C. M. Gorick, V. R. Breza, A. C. Debski, M. Hoch, T. Cruz, J. D. Samuels, J. Sheehan, D. Schlesinger, D. Moore, J. R. Lukens, P. Tvrdik, G. W. Miller, R. J. Price

This paper shows that focused ultrasound blood-brain barrier opening can stop and prevent the growth of cerebral cavernous malformations in mice.

bioRxiv · Jan 31, 2024 · PreprintBioengineering

Caspase-1 in Cx3cr1-expressing cells drives an IL-18-dependent T cell response that promotes parasite control during acute T. gondii infection

I. W. Babcock, L. A. Sibley, S. A. Labuzan, M. N. Cowan, I. Sethi, S. Alemu, M. A. Kovacs, J. R. Lukens, T. H. Harris

This study shows that caspase-1 in Cx3cr1-expressing cells drives IL-18 release, enhancing CD4+ T cell IFN-γ production and parasite control during acute T. gondii infection.

bioRxiv · Jan 29, 2024 · PreprintImmunology

Acute lymph node slices are a functional model system to study immunity ex vivo

M. C. Belanger, A. G. Ball, M. A. Catterton, A. W. L. Kinman, P. Anbaei, B. D. Groff, S. J. Melchor, J. R. Lukens, A. E. Ross, R. R. Pompano

This study validates live murine lymph node slices as a functional ex vivo model to study immune responses while preserving spatial organization and dynamic accessibility.

bioRxiv · Dec 28, 2020Immunology

Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection

S. J. Batista, K. M. Still, D. Johanson, J. A. Thompson, C. A. O'Brien, J. R. Lukens, T. Harris

bioRxiv · Jan 22, 2020Immunology