Author

J. A. Thompson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Evolutionary Biology· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Assay:metagenomics· 2 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. A. O'Brien· 3 shared S. J. Batista· 3 shared K. M. Still· 2 shared M. A. Kovacs· 2 shared M. N. Cowan· 2 shared T. H. Harris· 2 shared B. S. Richardson· 1 shared B. Yilmaz· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersImmunology

C. A. O'Brien

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Microglial STAT1-sufficiency is required for resistance to toxoplasmic encephalitis

M. N. Cowan, M. A. Kovacs, I. Sethi, I. W. Babcock, K. Still, S. J. Batista, C. A. O'Brien, J. A. Thompson, L. A. Sibley, S. A. Labuzan, T. H. Harris

This study shows that microglial STAT1 is essential for controlling T. gondii infection and preventing toxoplasmic encephalitis by regulating microglial activation and anti-parasitic functions.

bioRxiv · Jun 6, 2022Immunology

Differential and synergistic effects of low birth weight and Western diet on skeletal muscle vasculature, mitochondrial lipid metabolism and insulin signaling in male guinea pigs

K. Dunlop, O. Sarr, N. Stachura, L. Zhao, K. Nygard, J. A. Thompson, J. Hadway, B. S. Richardson, Y. Bureau, N. Borradaile, T.-Y. Lee, T. R. H. Regnault

bioRxiv · Oct 13, 2021Physiology

Glycan-Based Shaping Of The Microbiota During Primate Evolution

S. Singh, P. Bastos-Amador, J. A. Thompson, M. Truglio, B. Yilmaz, S. Cardoso, D. Sobral, M. P. Soares

The paper investigates how loss of GGTA1 function in primates affects host-microbiota interactions, finding that it reduces microbiota pathogenicity through IgA targeting of Gal-expressing bacteria.

bioRxiv · Feb 10, 2021Evolutionary Biology

Astrocytes promote a protective immune response to brain Toxoplasma gondii infection via IL-33-ST2 signaling

K. M. Still, S. J. Batista, C. A. O'Brien, O. O. Oyesola, S. Frueh, L. Webb, I. Smirnov, M. A. Kovacs, M. N. Cowan, N. W. Hayes, J. A. Thompson, E. D. Tait Wojno, T. H. Harris

This study shows that astrocytes use IL-33-ST2 signaling to promote protective immune responses against brain Toxoplasma gondii infection by recruiting anti-parasitic immune cells.

bioRxiv · May 7, 2020 · PreprintImmunology

Gasdermin-D-dependent IL-1α release from microglia promotes protective immunity during chronic Toxoplasma gondii infection

S. J. Batista, K. M. Still, D. Johanson, J. A. Thompson, C. A. O'Brien, J. R. Lukens, T. Harris

bioRxiv · Jan 22, 2020Immunology

A Bayesian framework for identifying consistent patterns of microbial abundance between body sites

R. Meier, J. A. Thompson, M. Chung, N. Zhao, K. T. Kelsey, D. S. Michaud, D. C. Koestler

The paper introduces a Bayesian framework to identify microbes with consistent abundance patterns between body sites related to a phenotypic variable, demonstrating its effectiveness using pancreatic cancer patient data.

bioRxiv · Jun 18, 2019Microbiology