Author

I. Uranga

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

J. Pardo· 2 shared M. Arias· 2 shared A. Annibaldi· 1 shared A. Craxton· 1 shared A. J. Kueh· 1 shared A. Linkermann· 1 shared A. Ramirez· 1 shared C. Carvajal Fraile· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

J. Pardo

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair

K. Martinez Lagunas, D. P. Savcigil, M. Zrilic, C. Carvajal Fraile, A. Craxton, E. Self, I. Uranga, D. de Miguel, M. Arias, S. Willenborg, M. Piekarek, M. C. Albert, K. Nugraha, I. Lisewski, E. Janakova, , A. Annibaldi

This study shows that cleavage of cFLIP by Caspase-8 limits cell death during viral infection and tissue injury, promoting tissue repair.

bioRxiv · Dec 15, 2022Cell Biology

Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis.

M. Arias, J. Pardo, M. Garzon, J. L. Sierra, L. Comas, L. Santiago, T. Khaliulina, I. Uranga, A. Ramirez, E. Tapia, E. Morte, S. Algarate, L. Couty, E. Camerer, P. I. Bird, , E. Galvez

This study shows that inhibiting Granzyme A reduces inflammation and improves survival in abdominal sepsis by decreasing proinflammatory markers without affecting bacterial load.

bioRxiv · Jun 5, 2020Immunology