Author

L. Santiago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Pardo· 2 shared M. Arias· 2 shared A. Ramirez· 1 shared A. S. Chawla· 1 shared C. J. Anderson· 1 shared C. Nguyen· 1 shared D. Dikovskaya· 1 shared E. Camerer· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

J. Pardo

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2 papers

Recent·Most cited

Distinct cell death pathways induced by granzymes collectively protect against intestinal Salmonella infection

A. S. Chawla, M. Vandereyken, M. Arias, L. Santiago, D. Dikovskaya, C. Nguyen, N. Skariah, N. Wenner, N. Golovchenko, S. Thomson, E. Ondari, M. Garzon-Tituana, C. J. Anderson, M. Bergkessel, J. C. D. Hinton, , M. Swamy

This study shows that granzymes A and B use distinct cell death pathways to protect against intestinal Salmonella infection by balancing bacterial growth and translocation.

bioRxiv · Nov 7, 2021Immunology

Granzyme A inhibition reduces inflammation and increases survival during abdominal sepsis.

M. Arias, J. Pardo, M. Garzon, J. L. Sierra, L. Comas, L. Santiago, T. Khaliulina, I. Uranga, A. Ramirez, E. Tapia, E. Morte, S. Algarate, L. Couty, E. Camerer, P. I. Bird, , E. Galvez

This study shows that inhibiting Granzyme A reduces inflammation and improves survival in abdominal sepsis by decreasing proinflammatory markers without affecting bacterial load.

bioRxiv · Jun 5, 2020Immunology