Author

D. de Miguel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

H. Walczak· 2 shared A. Annibaldi· 1 shared A. Craxton· 1 shared A. J. Kueh· 1 shared A. Linkermann· 1 shared B. J. Ferguson· 1 shared C. Carvajal Fraile· 1 shared C. Lefevre· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

H. Walczak

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Author profile →

2 papers

Recent·Most cited

Cleavage of cFLIP restrains cell death during viral infection and tissue injury and favors tissue repair

K. Martinez Lagunas, D. P. Savcigil, M. Zrilic, C. Carvajal Fraile, A. Craxton, E. Self, I. Uranga, D. de Miguel, M. Arias, S. Willenborg, M. Piekarek, M. C. Albert, K. Nugraha, I. Lisewski, E. Janakova, , A. Annibaldi

This study shows that cleavage of cFLIP by Caspase-8 limits cell death during viral infection and tissue injury, promoting tissue repair.

bioRxiv · Dec 15, 2022Cell Biology

LUBAC is required for RIG-I sensing of RNA viruses

H. C. Teague, C. Lefevre, E. Rieser, D. de Miguel, D. Patricio, M. Oliveira, D. S. Mansur, N. Irigoyen, H. Walczak, B. J. Ferguson

This study shows that LUBAC components HOIP and HOIL-1 are required for RIG-I sensing of RNA viruses, while SHARPIN is not, highlighting LUBAC's role in antiviral immunity.

bioRxiv · Feb 24, 2022Immunology