Author

I. V. Akhrymuk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

K. Kehn-Hall· 2 shared A. A. Waheed· 1 shared A. M. Klingler· 1 shared B. Hetrick· 1 shared B. M. Henry· 1 shared D. Dabbagh· 1 shared E. O. Freed· 1 shared F. Noe· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

K. Kehn-Hall

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2

N. P. Azouz, A. M. Klingler, V. Callahan, I. V. Akhrymuk, K. Elez, L. Raich, B. M. Henry, J. L. Benoit, S. W. Benoit, F. Noe, K. Kehn-Hall, M. E. Rothenberg

This study identifies alpha 1 antitrypsin (A1AT) as a TMPRSS2 inhibitor that limits SARS-CoV-2 dissemination by inhibiting extracellular proteases involved in viral entry.

bioRxiv · May 4, 2020Microbiology

PSGL-1 inhibits the virion incorporation of SARS-CoV and SARS-CoV-2 spike glycoproteins and impairs virus attachment and infectivity

S. He, A. A. Waheed, B. Hetrick, D. Dabbagh, I. V. Akhrymuk, K. Kehn-Hall, E. O. Freed, Y. Wu

The paper shows PSGL-1 inhibits SARS-CoV and SARS-CoV-2 spike glycoprotein incorporation into pseudovirions, blocking virus attachment and infectivity.

bioRxiv · May 1, 2020 · PreprintMicrobiology