Obesity Potentiates TH2 Immunopathology via Dysregulation of PPAR
S. Bapat, Y. Liang, S. Liu, L.-j. Zhang, I. Vogel, D. J. Marr, C. Zhou, E. J. Choi, C. Chang, N. He, M. LeBlanc, I.-k. Lee, J. M. Suh, L. E. Crotty Alexander, C. Liddle, , Y. Zheng
This study shows obesity increases TH2 immunopathology by disrupting PPARγ in T cells, and TZDs can protect against this effect in obese mice.
bioRxiv · Oct 31, 2019 · PreprintImmunology