Author

I.-K. Lee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Marson· 1 shared A. R. Atkins· 1 shared A. Y. Ting· 1 shared C. Chang· 1 shared C. Kwak· 1 shared C. Liddle· 1 shared C. Zhou· 1 shared D. J. Marr· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperImmunology

A. Marson

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Author profile →

3 papers

Recent·Most cited

Split-TurboID enables contact-dependent proximity labeling in cells

K. F. Cho, T. C. Branon, S. Rajeev, T. Svinkina, N. D. Udeshi, T. Thoudam, C. Kwak, H.-W. Rhee, I.-K. Lee, S. A. Carr, A. Y. Ting

Split-TurboID enables proximity labeling at organelle contact sites by splitting the TurboID enzyme and reconstituting it at these sites, identifying over 100 endogenous proteins.

Proceedings of the National Academy of Sciences · May 18, 2020Peer-reviewedCell Biology

Obesity Potentiates TH2 Immunopathology via Dysregulation of PPAR

S. Bapat, Y. Liang, S. Liu, L.-j. Zhang, I. Vogel, D. J. Marr, C. Zhou, E. J. Choi, C. Chang, N. He, M. LeBlanc, I.-k. Lee, J. M. Suh, L. E. Crotty Alexander, C. Liddle, , Y. Zheng

This study shows obesity increases TH2 immunopathology by disrupting PPARγ in T cells, and TZDs can protect against this effect in obese mice.

bioRxiv · Oct 31, 2019 · PreprintImmunology

SMAD3 Determines Conventional versus Plasmacytoid Dendritic Cell Fates

J.-H. Yoon, E. Bae, K. Sudo, J. S. Han, S. H. Park, S. Nakae, T. Yamashita, I.-K. Lee, J. H. Ju, I. Matsumoto, T. Sumida, M. Kuroda, K. Miyazawa, M. Kato, M. Mamura

This study identifies SMAD3 as a key regulator determining conventional DC versus plasmacytoid DC differentiation through distinct gene regulatory mechanisms.

bioRxiv · Jul 25, 2019 · PreprintImmunology