Author

I. W. Chalmers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Brancale· 1 shared C. A. Celatka· 1 shared C. Grunau· 1 shared C. M. Fitzsimmons· 1 shared D. Lassalle· 1 shared E. M. Tukahebwa· 1 shared G. Padalino· 1 shared H. A. Dickinson· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

A. Brancale

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Author profile →

2 papers

Recent·Most cited

Protective human IgE responses are promoted by comparable life-cycle dependent Tegument Allergen-Like protein expression in Schistosoma haematobium and Schistosoma mansoni infection

R. Oettle, H. A. Dickinson, C. M. Fitzsimmons, M. Sacko, E. M. Tukahebwa, I. W. Chalmers, S. Wilson

This paper characterizes the Tegument Allergen-Like (TAL) protein family in Schistosoma haematobium and shows cross-reactive IgE responses similar to those observed in S. mansoni infection.

bioRxiv · Dec 2, 2022 · PreprintImmunology

Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) is a druggable target involved in parasite survival, oviposition and stem cell proliferation.

G. Padalino, C. A. Celatka, H. Y. Rienhoff, J. H. Kalin, P. A. Cole, D. Lassalle, C. Grunau, I. W. Chalmers, A. Brancale, K. F. Hoffmann

This study investigates the anti-schistosomal activity of HsLSD1 inhibitors on S. mansoni life cycle stages and identifies compound 33 as effective against parasite survival, oviposition, and stem cell proliferation.

bioRxiv · Sep 17, 2020 · PreprintMicrobiology