Author

I. Yurgelonis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1

Frequent Co-Authors

Y. Zhu· 2 shared A. A. Lee· 1 shared A. Balesano· 1 shared A. Behzadi· 1 shared A. Ephron· 1 shared A. Gribenko· 1 shared A. S. Anderson· 1 shared A. S. Kalgutkar· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

Y. Zhu

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model

M. R. Garnsey, M. C. Robinson, L. T. Nguyen, R. Cardin, J. Tillotson, E. Mashalidis, Y. Aijia, L. Aschenbrenner, A. Balesano, A. Behzadi, B. Boras, J. S. Chang, H. Eng, A. Ephron, T. Foley, , A. A. Lee

This study identifies potent SARS-CoV-2 PLpro inhibitors using machine learning, showing efficacy in a mouse model of COVID-19.

bioRxiv · Jan 26, 2024 · PreprintMicrobiology

Nirmatrelvir, an orally active Mpro inhibitor, is a potent inhibitor of SARS-CoV-2 Variants of Concern

D. K. Rai, I. Yurgelonis, P. McMonagle, H. A. Rothan, L. Hao, A. Gribenko, E. Titova, B. Kreiswirth, K. M. White, Y. Zhu, A. S. Anderson, R. D. Cardin

This paper evaluates the antiviral activity of Nirmatrelvir against multiple SARS-CoV-2 variants using qRT-PCR in VeroE6 cells, showing potent inhibition across all tested variants.

bioRxiv · Jan 17, 2022Microbiology