Author

A. S. Kalgutkar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Y. Liu· 2 shared A. A. Lee· 1 shared A. Balesano· 1 shared A. Behzadi· 1 shared A. Ephron· 1 shared A. M. Mathiowetz· 1 shared A. R. Saxena· 1 shared B. Boras· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

Y. Liu

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model

M. R. Garnsey, M. C. Robinson, L. T. Nguyen, R. Cardin, J. Tillotson, E. Mashalidis, Y. Aijia, L. Aschenbrenner, A. Balesano, A. Behzadi, B. Boras, J. S. Chang, H. Eng, A. Ephron, T. Foley, , A. A. Lee

This study identifies potent SARS-CoV-2 PLpro inhibitors using machine learning, showing efficacy in a mouse model of COVID-19.

bioRxiv · Jan 26, 2024 · PreprintMicrobiology

A small-molecule oral agonist of the human glucagon-like peptide-1 receptor

D. A. Griffith, D. J. Edmonds, J.-P. Fortin, A. S. Kalgutkar, J. B. Kuzmiski, P. M. Loria, A. R. Saxena, S. W. Bagley, C. Buckeridge, J. M. Curto, D. R. Derksen, J. M. Dias, M. C. Griffor, S. Han, V. M. Jackson, , D. A. Tess

The paper describes an orally bioavailable small molecule agonist of the GLP-1R that lowers blood glucose in humans.

bioRxiv · Sep 29, 2020Pharmacology & Toxicology