Author

I.-T. Chow

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:metagenomics· 1

Frequent Co-Authors

W. W. Kwok· 2 shared A. HEIT· 1 shared A. Raisingani· 1 shared C. Brady· 1 shared C. Gooley· 1 shared C. R. Kahn· 1 shared D. S. W. TAN· 1 shared E. ALTINDIS· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

W. W. Kwok

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Author profile →

3 papers

Recent·Most cited

Large-scale statistical mapping of T-cell receptor β sequences to Human Leukocyte Antigens

H. J. Zahid, R. Taniguchi, P. Ebert, I.-T. Chow, C. Gooley, J. Lv, L. Pisani, M. Rusnak, R. Elyanow, H. Takamatsu, W. Zhou, J. Greissl, H. Robins, J. M. Carlson

The paper maps T-cell receptor β sequences to specific HLA allotypes using population-level TCR repertoire data, enabling accurate HLA imputation and revealing insights into TCR-HLA interactions.

bioRxiv · Apr 1, 2024 · PreprintImmunology

A Gut Microbial Peptide and Molecular Mimicry in the Pathogenesis of Type 1 Diabetes

K. Girdhar, Q. Huang, I.-T. Chow, C. Brady, A. Raisingani, P. Autissier, M. A. Atkinson, W. W. Kwok, C. R. Kahn, E. ALTINDIS

This paper identifies a gut microbial peptide that mimics an insulin epitope and contributes to Type 1 Diabetes pathogenesis by triggering immune cross-reactivity and accelerating disease onset in mice.

bioRxiv · Oct 22, 2020Immunology

Bystander CD4+ T cells infiltrate human tumors and are phenotypically distinct

y. SIMONI, S. LI, S. ZHUANG, A. HEIT, S.-L. KOO, I.-T. CHOW, W. W. KWOK, I. B. TAN, D. S. W. TAN, E. W. NEWELL

The paper identifies bystander CD4+ T cells in human tumors, showing they are phenotypically distinct and express CD39, correlating with CD8+ TILs specific for non-cancer antigens.

bioRxiv · Jul 15, 2020 · PreprintImmunology