Author

Irene Zebochin

King's College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:electronic health records· 1

Frequent Co-Authors

Franziska DenkiD· 4 shared Leonie S. TaamsiD· 4 shared Yuening Li· 4 shared Laura FedeleiD· 3 shared Amy LockiD· 2 shared Julia M. Vlachaki WalkeriD· 2 shared Oliver BrüstleiD· 2 shared Pascal RödereriD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersNeuroscience

Franziska DenkORCID

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4 papers

Recent·Most cited

LIF is a pro-algesic mediator in human and mouse models of arthritis-related pain

Rosie Ross, Yuening Li, Julia M. Vlachaki Walker, Mosab Ali Awadelkareem, Irene Zebochin, George L. Goodwin, Alina-Cristina Marin, Teodora Trendafilova, Innes Montague, Zoe Rutter‐Locher, Sarah E. Ryan, Friederike Baldeweg, Katja Freytag, Rophi Condor, Natalie Arridge, , Leonie S. Taams

This study identifies LIF as a key pro-algesic cytokine in arthritis-related pain, showing its role in neuronal signalling and pain-like behaviours in human and mouse models.

bioRxiv · Oct 18, 2026 · PreprintNeuroscience

A role for fibroblast and mural cell subsets in a nerve ligation model of neuropathic pain.

Sara Villa‐Hernández, Julia M. Vlachaki Walker, Zoe Lee Hore, Laura Fedele, Irene Zebochin, Yuening Li, Harvey Davis, Takashi Kanda, Fumitaka Shimizu, Leonie S. Taams, Franziska Denk

This paper identifies Pdgfrb+ fibroblast and mural cells as contributors to neuropathic pain by showing their increased numbers and expression of pro-algesic mediators in a mouse model.

Brain Behavior and Immunity · May 15, 2025Peer-reviewedNeuroscience

Blockade of rheumatoid arthritis synovial fluid-induced sensory neuron activation by JAK inhibitors

Yuening Li, E. H. Gray, Rosie Ross, Irene Zebochin, Amy Lock, Laura Fedele, Louisa Janice Kamajaya, Rebecca J Marrow, Sarah E. Ryan, Pascal Röderer, Oliver Brüstle, Susan John, Franziska Denk, Leonie S. Taams

This study shows JAK inhibitors block RA synovial fluid-induced sensory neuron activation by inhibiting STAT3 phosphorylation and pain gene expression.

JCI Insight · May 15, 2025Peer-reviewedImmunology

Modelling inflammation-induced peripheral sensitization in a dish - more complex than expected?

Yuening Li, Amy Lock, Laura Fedele, Irene Zebochin, Alba Sabate, Matthew R. Siddle, Silvia Cainarca, Pascal Röderer, Katharina Montag, Paola Tarroni, Oliver Brüstle, Tanya J. Shaw, Leonie S. Taams, Franziska Denk

The paper investigates the effects of inflammatory soup on sensory neuron excitability using human and mouse models, finding minimal changes and suggesting that in vitro modeling of peripheral sensitization is complex.

Pain · Feb 25, 2025Peer-reviewedNeuroscience