George L. Goodwin

This study identifies LIF as a key pro-algesic cytokine in arthritis-related pain, showing its role in neuronal signalling and pain-like behaviours in human and mouse models.

This study uses in vivo calcium imaging to show that DRG stimulation in mice primarily activates large-sized sensory neurons, with no change in response magnitude but a temporary reduction in mechanical stimulation responses.

This study uses in vivo calcium imaging and home cage monitoring to assess joint neuron activity and locomotor behavior in mouse arthritis models, finding increased spontaneous activity in AIA mice but not PMX mice.

This study uses in vivo calcium imaging to show that satellite glial cells show increased activity in painful states, with some signals linked to neuronal firing and others occurring independently.

This paper assesses spontaneous sensory neuron activity using in vivo calcium imaging and develops a machine learning algorithm to predict spontaneous activity with high accuracy across different pain models and labs.

This review examines spontaneous activity in peripheral sensory nerves in neuropathic pain, finding broad agreement on its presence but highlighting variability and uncertainty due to methodological differences.

This study investigates Nav1.7's role in axonal propagation in nociceptors using sodium channel blockers in mice, finding it essential in about 2/3 of C-fibre neurons and a lower proportion of muscle-innervating neurons.