Author

Irwin M. Arias

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Agustina L. LafuenteiD· 1 shared Alba Jiménez‐PanizoiD· 1 shared Andrea Alegre‐MartíiD· 1 shared Annabel F. ValledoriD· 1 shared Diana A. StavrevaiD· 1 shared Diego M. PresmaniD· 1 shared Eva Estébanez‐PerpiñáiD· 1 shared Gordon L. HageriD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Agustina L. LafuenteORCID

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1 paper

Recent·Most cited

Bile acids target an exposed cavity in the glucocorticoid receptor modulating receptor self-assembly, chromatin binding and transcriptional activity

Alba Jiménez‐Panizo, Thomas A. Johnson, Kaustubh Wagh, Andrea Alegre‐Martí, Inés Montoya-Novoa, Agustina L. Lafuente, Ulrich Eckhard, Luis Angel Rodríguez‐Lumbreras, Le Hoang, Martín Stortz, Montserrat Abella, Ido Goldstein, Annabel F. Valledor, Lyuba Varticovski, Irwin M. Arias, , Eva Estébanez‐Perpiñá

This study shows bile acids bind to an exposed cavity on the glucocorticoid receptor, affecting its self-assembly and transcriptional activity.

bioRxiv · May 13, 2025 · PreprintMolecular Biology