Author

Isabelle L. Jones

Colorado State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Gregory T. RobertsoniD· 2 shared Allison A. Bauman· 1 shared Anne J. Lenaerts· 1 shared Bernd MeibohmiD· 1 shared Brendan K. PodelliD· 1 shared Camile Moore· 1 shared Chuangqi WangiD· 1 shared Courtney Hastings· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Gregory T. RobertsonORCID

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2 papers

Recent·Most cited

Adaptive immunity shapes baseline physiology of M. tuberculosis in high-dose versus low-dose infection BALB/c mouse drug treatment models

Jo Hendrix, Reem Al Mubarak, Karen Rossmassler, Holly Nielsen, Elizabeth Wynn, Camile Moore, Isabelle L. Jones, Martin I. Voskuil, Brendan K. Podell, Gregory T. Robertson, Chuangqi Wang, Nicholas D. Walter

This study compares M. tuberculosis physiology in high-dose and low-dose infection models, showing how adaptive immunity affects bacterial metabolism and drug efficacy.

Antimicrobial Agents and Chemotherapy · Jul 31, 2026Peer-reviewedGenomics

Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis

Allison A. Bauman, Jansy P. Sarathy, Firat Kaya, Lisa M. Massoudi, Michael S. Scherman, Courtney Hastings, Jiuyu Liu, Min Xie, Elizabeth J. Brooks, Michelle E. Ramey, Isabelle L. Jones, Noalani D. Benedict, Madelyn R. Maclaughlin, Jake A. Miller-Dawson, Samanthi L. Waidyarachchi, , Gregory T. Robertson

This study shows that MBX-4888A, a spectinamide, shortens tuberculosis treatment in murine models by improving tissue distribution and working well with rifampin and pyrazinamide.

bioRxiv · May 13, 2024Microbiology