Author

Jo Hendrix

United States Department of Veterans AffairsORCID 0000-0001-9029-2390Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Organism:mouse· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Gregory T. RobertsoniD· 3 shared Karen RossmassleriD· 3 shared Martin I. VoskuiliD· 3 shared Nicholas D. WalteriD· 3 shared Reem Al MubarakiD· 3 shared Camille M. MooreiD· 2 shared Elizabeth A. WynniD· 2 shared Adeline Bateman· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersGenomics

Gregory T. RobertsonORCID

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3 papers

Recent·Most cited

GenomicsAntimicrobial Agents and ChemotherapyPeer-reviewedJul 31, 2026

Adaptive immunity shapes baseline physiology of M. tuberculosis in high-dose versus low-dose infection BALB/c mouse drug treatment models

Jo Hendrix, Reem Al Mubarak, Karen Rossmassler…·Nicholas D. Walter

This study compares M. tuberculosis physiology in high-dose and low-dose infection models, showing how adaptive immunity affects bacterial metabolism and drug efficacy.

DOI 10.1128/aac.00421-26

mousebulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivPreprintFeb 25, 2025

Physiologic recovery of Mycobacterium tuberculosis from drug injury: A molecular study of post antibiotic effect in mice

Jo Hendrix, Reem Al Mubarak, Adeline Bateman…·Nicholas D. Walter

This study investigates the physiologic recovery of Mycobacterium tuberculosis in mice after antibiotic treatment, finding that recovery is slow, sequential, and incomplete, with longer treatment leading to slower recovery.

3 citations

mousebulk RNA-seq

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GenomicsbioRxivPreprintFeb 24, 2025

Deconvoluting drug interactions based on M. tuberculosis physiologic processes:Transcriptional disaggregation of the BPaL regimen in vivo

Elizabeth A. Wynn, Christian Dide-Agossou, Reem Al Mubarak…·Nicholas D. Walter

The paper uses SEARCH-TB to analyze drug interactions in M. tuberculosis by measuring transcriptional responses to the BPaL regimen in vivo, showing complex effects of drug combinations.

2 citations

mousebulk RNA-seq

𝕏 PostBluesky