Author

Isabelle Meneau

University Hospital Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Frank BlaseriD· 2 shared Alice ReschignaiD· 1 shared Antonia Fottner· 1 shared Christian GrimmiD· 1 shared Claudia Matter· 1 shared Cornelia Imsand· 1 shared Diego S. Fajardo· 1 shared Dina Yehia Otify· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Frank BlaserORCID

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2 papers

Recent·Most cited

A novel multiplex RNAi therapy simultaneously targets Hif1a and Hif2a to defy retinal degeneration in two models of AMD

Lynn J. A. Ebner, Cornelia Imsand, Duygu Karademir, Florian Peters, Eva Kiessling, Antonia Fottner, Claudia Matter, Diego S. Fajardo, Luca Merolla, Gabriele M Wögenstein, Ioanna Tsioti, Larissa P. Govers, Frank Blaser, Isabelle Meneau, Sanford L. Boye, , Marijana Samardzija

This paper develops a dual-acting RNAi therapy targeting Hif1a and Hif2a to protect retinal cells in AMD models, showing superior efficacy compared to single-target therapies.

Molecular Therapy · Sep 27, 2025Peer-reviewedNeuroscience

CRISPRa-mediated activation of genes associated with inherited retinal dystrophies in acutely isolated human cells for diagnostic purposes

Valentin Johannes Weber, Alice Reschigna, Maximilian J. Gerhardt, Klara Sonnie Hinrichsmeyer, Dina Yehia Otify, Thomas Heigl, Frank Blaser, Isabelle Meneau, Martin Biel, Stylianos Michalakis, Elvir Bećirović

The paper uses CRISPRa to activate IRD-linked genes in PBMCs to detect transcripts for improved genetic diagnosis of inherited retinal dystrophies.

bioRxiv · Nov 29, 2024 · PreprintGenetics