NHR-8 regulated P-glycoproteins uncouple xenobiotic stress resistance from longevity in chemosensory C. elegans mutants
Gabriel A Guerrero, Maxime J. Derisbourg, Laura E. Wester, Marco Gordia, J Eike Dinort, María J. Alonso, Matías Daniel Hartman, Klara Schilling, Felix A.M.C. Mayr, Ryan J. Lu, Bérénice Anath Benayoun, Martin Sebastian Denzel
The paper identifies that NHR-8 regulates P-glycoproteins in C. elegans, uncoupling xenobiotic stress resistance from longevity in osm-3 mutants.
eLife · Aug 27, 2021Peer-reviewedGenetics