Author

Klara Schilling

Max Planck Institute for Biology of AgeingORCID 0000-0002-1294-2201Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam AntebiiD· 1 shared Alex ZaufeliD· 1 shared Anna Löhrke· 1 shared Bérénice Anath BenayouniD· 1 shared Felix A.M.C. MayriD· 1 shared Gabriel A GuerreroiD· 1 shared Hans‐Joachim KnölkeriD· 1 shared J Eike Dinort· 1 shared

Activity by Year

2021-2026 · peak 1/yr

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10 top collaborators · 20 mutual co-author links

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1 shared paperGenetics

Adam AntebiORCID

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2 papers

Recent·Most cited

mTOR regulates longevity through a bile-acid like hormonal mechanism and DHS- 26/DHRS1

Klara Schilling, Alex Zaufel, Kaylee M Morris, Anna Löhrke, Ratni Saini, Hans‐Joachim Knölker, Tarek Moustafa, Adam Antebi

This study identifies mTOR's role in longevity through a bile-acid-like hormonal mechanism involving DHS-26/DHRS1 in C. elegans and mammals.

bioRxiv · May 17, 2026 · PreprintGenetics

NHR-8 regulated P-glycoproteins uncouple xenobiotic stress resistance from longevity in chemosensory C. elegans mutants

Gabriel A Guerrero, Maxime J. Derisbourg, Laura E. Wester, Marco Gordia, J Eike Dinort, María J. Alonso, Matías Daniel Hartman, Klara Schilling, Felix A.M.C. Mayr, Ryan J. Lu, Bérénice Anath Benayoun, Martin Sebastian Denzel

The paper identifies that NHR-8 regulates P-glycoproteins in C. elegans, uncoupling xenobiotic stress resistance from longevity in osm-3 mutants.

eLife · Aug 27, 2021Peer-reviewedGenetics